Engineered antibodies and their fragments are invaluable instruments for an enormous vary of biotechnological and pharmaceutical purposes. However, they’re going through growing competitors from a new generation of protein display scaffolds, particularly chosen for binding just about any goal. Some of them have already entered medical trials.
Most of these nonimmunoglobulin proteins are concerned in pure binding occasions and have amazingly various origins, frameworks, and capabilities, together with even intrinsic enzyme exercise.
In many respects, they’re superior over antibody-derived affinity molecules and provide an ever-extending arsenal of instruments for, e.g., affinity purification, protein microarray expertise, bioimaging, enzyme inhibition, and potential drug supply.
Blue Particle Array Kit |
PAK-5067-10K |
Spherotech |
10X1 mL |
EUR 939 |
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone. |
Blue Particle Array Kit |
PAK-5067-5A |
Spherotech |
5X1 mL |
EUR 563 |
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone. |
Blue Particle Array Kit |
PAK-5067-5B |
Spherotech |
5X1 mL |
EUR 563 |
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone. |
Blue Particle Array Kit |
PAK-7067-9K |
Spherotech |
9X1 mL |
EUR 939 |
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone. |
CA125 antibody array kit |
VArk-Lsx008 |
Creative Biolabs |
1 mg |
EUR 664 |
Description: CA125 can be used as a tumor marker to identify the type of tumor and check if the treatment is working. |
Ferritin antibody array kit |
VArk-Lsx009 |
Creative Biolabs |
1 mg |
EUR 419 |
Description: Used for detection of Ferritin |
Microalbuminuria antibody array kit |
VArk-Lsx010 |
Creative Biolabs |
1 mg |
EUR 419 |
Description: Used to detect early signs of kidney damage |
Cancer MicroRNA qPCR Array |
RA610A-1 |
SBI |
10 profiles |
EUR 1172 |
|
Human Cell Array I |
17-601 |
ProSci |
1 pack |
EUR 191 |
Description: Human cell lines (HEK293, A-431, A549, Hela S3, Hep G2 and MCF7) |
Human Cell Array II |
17-602 |
ProSci |
1 pack |
EUR 191 |
Description: Human cell lines (HL-60, Jurkat, K-562, MOLT-4, Raji and THP-1) |
FDA Standard Tissue Array |
T8234701-1 |
Biochain |
1 slides |
EUR 214 |
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool. |
FDA Standard Tissue Array |
T8234701-5 |
Biochain |
5 slides |
EUR 654 |
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool. |
Paraffin Tissue Section Array - Human Adult Normal Tissue, Array I (64 Specimens) |
T8234708-2 |
Biochain |
2 slides |
EUR 307 |
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool. |
Paraffin Tissue Section Array - Human Adult Normal Tissue, Array I (64 Specimens) |
T8234708-5 |
Biochain |
5 slides |
EUR 579 |
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool. |
As wonderful supporting frameworks for the presentation of polypeptide libraries, they are often subjected to highly effective in vitro or in vivo choice and evolution methods, enabling the isolation of high-affinity binding reagents.
This article evaluations the generation of these novel binding reagents, describing validated and superior different scaffolds in addition to the latest nonimmunoglobulin libraries.
Characteristics of these protein scaffolds in phrases of structural stability, tolerance to a number of substitutions, ease of expression, and subsequent purposes as particular focusing on molecules are mentioned.
Furthermore, this evaluation exhibits the shut linkage between these novel protein instruments and the continuously growing display, choice, and evolution methods utilizing phage display, ribosome display, mRNA display, cell floor display, or IVC (in vitro compartmentalization).
Ribosome-inactivating protein gynostemmin Antibody |
20-abx300943 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
-
EUR 182.00
-
EUR 300.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Ribosome-inactivating protein karasurin-C Antibody |
1-CSB-PA326146HA01TIF |
Cusabio |
|
|
|
Description: A polyclonal antibody against Ribosome-inactivating protein karasurin-C. Recognizes Ribosome-inactivating protein karasurin-C from Trichosanthes kirilowii. This antibody is Unconjugated. Tested in the following application: ELISA |
Ribosome-inactivating protein bryodin I Antibody |
1-CSB-PA339327LA01BMR |
Cusabio |
|
|
|
Description: A polyclonal antibody against Ribosome-inactivating protein bryodin I. Recognizes Ribosome-inactivating protein bryodin I from Bryonia dioica. This antibody is Unconjugated. Tested in the following application: ELISA |
Ribosome-inactivating protein alpha-trichosanthin Antibody |
1-CSB-PA357829HA01TIF |
Cusabio |
|
|
|
Description: A polyclonal antibody against Ribosome-inactivating protein alpha-trichosanthin. Recognizes Ribosome-inactivating protein alpha-trichosanthin from Trichosanthes kirilowii. This antibody is Unconjugated. Tested in the following application: ELISA |
Silene chalcedonica Ribosome-inactivating protein lychnin |
1-CSB-YP307648LKN |
Cusabio |
-
EUR 679.00
-
EUR 335.00
-
EUR 2172.00
-
EUR 1051.00
-
EUR 1442.00
-
EUR 435.00
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Silene chalcedonica Ribosome-inactivating protein lychnin expressed in Yeast |
Drimia maritima Ribosome-inactivating protein charybdin |
1-CSB-YP308125DEZ |
Cusabio |
-
EUR 679.00
-
EUR 335.00
-
EUR 2172.00
-
EUR 1051.00
-
EUR 1442.00
-
EUR 435.00
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Drimia maritima Ribosome-inactivating protein charybdin expressed in Yeast |
Recombinant Ribosome Binding Protein 1 (RRBP1) |
4-RPC770Hu01 |
Cloud-Clone |
-
EUR 548.00
-
EUR 250.00
-
EUR 1780.00
-
EUR 660.00
-
EUR 1220.00
-
EUR 430.00
-
EUR 4300.00
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Human Ribosome Binding Protein 1 expressed in: E.coli |
Silene chalcedonica Ribosome-inactivating protein lychnin |
1-CSB-EP307648LKN |
Cusabio |
-
EUR 611.00
-
EUR 309.00
-
EUR 1827.00
-
EUR 939.00
-
EUR 1218.00
-
EUR 397.00
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Silene chalcedonica Ribosome-inactivating protein lychnin expressed in E.coli |
Drimia maritima Ribosome-inactivating protein charybdin |
1-CSB-EP308125DEZ |
Cusabio |
-
EUR 611.00
-
EUR 309.00
-
EUR 1827.00
-
EUR 939.00
-
EUR 1218.00
-
EUR 397.00
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Drimia maritima Ribosome-inactivating protein charybdin expressed in E.coli |
Ribosome-Binding Protein 1 (RRBP1) Antibody |
20-abx126500 |
Abbexa |
-
EUR 411.00
-
EUR 592.00
-
EUR 182.00
-
EUR 314.00
|
- 100 ul
- 200 ul
- 20 ul
- 50 ul
|
|
Ribosome Biogenesis Regulator Homolog (RRS1) Antibody |
20-abx115342 |
Abbexa |
|
|
|
Ribosome Biogenesis Protein TSR1 (TSR1) Antibody |
20-abx116326 |
Abbexa |
|
|
|
Here, we predict the vital function of these novel binding reagents as a toolkit for biotechnological and biomedical purposes.

A new generation of protein display scaffolds for molecular recognition.
Recombinant Aspergillus fumigatus allergens: from the nucleotide sequences to medical purposes.
Members of the genus Aspergillus are opportunistic pathogens for cold- and warm-blooded animals. They are related to a formidable spectrum of illnesses in people, starting from benign colonization of the lung to life-threatening illnesses akin to invasive aspergillosis or allergic bronchopulmonary aspergillosis (ABPA). Aspergillus fumigatus is the etiological agent recognized in most of the Aspergillus-related human illnesses and is subsequently of explicit medical relevance.
Aspergillus fumigatus PCR kit |
PCR-VH002-48D |
Bioingentech |
50T |
EUR 453 |
Aspergillus fumigatus PCR kit |
PCR-VH002-96D |
Bioingentech |
100T |
EUR 572 |
Cellulase from Aspergillus niger |
abx082085-1g |
Abbexa |
1 g |
EUR 189 |
|
Cellulase from Aspergillus niger |
20-abx082478 |
Abbexa |
|
|
|
Inactivated Aspergillus Fumigatus Antigen |
VAng-Wyb3743-1mg |
Creative Biolabs |
1 mg |
EUR 5657 |
Description: Aspergillus Fumigatus, natural antigen. |
Asp f 3, Aspergillus |
LF-P0503 |
Abfrontier |
0.1 mg |
EUR 350 |
Description: Asp f 3, Aspergillus protein |
Asp f 3, Aspergillus |
LF-P0503A |
Abfrontier |
0.5 mg |
EUR 1247 |
Description: Asp f 3, Aspergillus protein |
Asp f 3, Aspergillus |
LF-P0503B |
Abfrontier |
1 mg |
EUR 1998 |
Description: Asp f 3, Aspergillus protein |
Andrastin A, Aspergillus fumigatus |
2149-1000 |
Biovision |
|
EUR 588 |
Andrastin A, Aspergillus fumigatus |
2149-250 |
Biovision |
|
EUR 229 |
Aspergillus Fumigatus IgM ELISA Kit |
DEIA314 |
Creative Diagnostics |
96T |
EUR 611 |
Description: The Aspergillus fumigatus IgM Antibody ELISA Test Kit has beendesigned for the detection and the quantitative determination of specificIgM antibodies against Aspergillus fumigatus in serum and plasma. |
Aspergillus spp. (A. spp.) Antibody |
abx414358-025mg |
Abbexa |
0.25 mg |
EUR 648 |
|
Aspergillus fumigatus RT PCR kit |
RTq-VH002-100D |
Bioingentech |
100T |
EUR 717 |
Aspergillus fumigatus RT PCR kit |
RTq-VH002-150D |
Bioingentech |
150T |
EUR 808 |
Aspergillus fumigatus RT PCR kit |
RTq-VH002-50D |
Bioingentech |
50T |
EUR 598 |
Aspergillus niger RT PCR kit |
RTq-A530-100D |
Bioingentech |
100T |
EUR 717 |
A main drawback within the analysis of A. fumigatus-related problems arises from the shortage of standardized fungal extracts.
The allergenicity of business A. fumigatus extracts is dependent upon many elements together with the pressure used, progress circumstances, harvesting and extraction procedures hampering the event of diagnostic reagents appropriate for the discrimination between A. fumigatus-related illnesses.
Molecular DNA/RNA applied sciences and biotechnological procedures enable cloning, characterization and manufacturing of giant quantities of single, extremely pure allergens. The growth of phage floor display applied sciences for cloning cDNAs has accelerated the isolation of candidate cDNAs encoding allergens.
Screening of an A. fumigatus cDNA library displayed on the floor of phage M13 allowed characterization and manufacturing of a panel of allergens recognized as proteins with identified organic perform or as allergens with out sequence homology to identified proteins. They belong to 2 practical classes: secreted and cytoplasmic proteins. Secreted allergens are acknowledged by serum IgE of A.
fumigatus-sensitized people with or with out ABPA, whereas nonsecreted allergens are solely acknowledged by serum IgE of ABPA sufferers. The dissection of IgE-mediated immune responses to single A.
Porcine Immunoglobulin E (IgE) ELISA Kit |
DLR-IgE-p-48T |
DL Develop |
48T |
EUR 547 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Porcine Immunoglobulin E (IgE) in samples from serum, plasma or other biological fluids. |
Porcine Immunoglobulin E (IgE) ELISA Kit |
DLR-IgE-p-96T |
DL Develop |
96T |
EUR 715 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Porcine Immunoglobulin E (IgE) in samples from serum, plasma or other biological fluids. |
Rat Immunoglobulin E (IgE) ELISA Kit |
DLR-IgE-Ra-48T |
DL Develop |
48T |
EUR 508 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Rat Immunoglobulin E (IgE) in samples from serum, plasma or other biological fluids. |
Rat Immunoglobulin E (IgE) ELISA Kit |
DLR-IgE-Ra-96T |
DL Develop |
96T |
EUR 661 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Rat Immunoglobulin E (IgE) in samples from serum, plasma or other biological fluids. |
Human Immunoglobulin E (IgE) ELISA Kit |
RDR-IgE-Hu-48Tests |
Reddot Biotech |
48 Tests |
EUR 500 |
Human Immunoglobulin E (IgE) ELISA Kit |
RDR-IgE-Hu-96Tests |
Reddot Biotech |
96 Tests |
EUR 692 |
Mouse Immunoglobulin E (IgE) ELISA Kit |
RDR-IgE-Mu-48Tests |
Reddot Biotech |
48 Tests |
EUR 511 |
Mouse Immunoglobulin E (IgE) ELISA Kit |
RDR-IgE-Mu-96Tests |
Reddot Biotech |
96 Tests |
EUR 709 |
Porcine Immunoglobulin E (IgE) ELISA Kit |
RDR-IgE-p-48Tests |
Reddot Biotech |
48 Tests |
EUR 580 |
Porcine Immunoglobulin E (IgE) ELISA Kit |
RDR-IgE-p-96Tests |
Reddot Biotech |
96 Tests |
EUR 807 |
Rat Immunoglobulin E (IgE) ELISA Kit |
RDR-IgE-Ra-48Tests |
Reddot Biotech |
48 Tests |
EUR 534 |
Rat Immunoglobulin E (IgE) ELISA Kit |
RDR-IgE-Ra-96Tests |
Reddot Biotech |
96 Tests |
EUR 742 |
Human IgE |
E61I022 |
EnoGene |
100ug |
EUR 343 |
IgE Protein |
abx069987-1ml |
Abbexa |
1 ml |
EUR 453 |
|
IgE Protein |
abx069988-100ug |
Abbexa |
100 ug |
EUR 926 |
|
Human IgE |
31R-1089 |
Fitzgerald |
1 mg |
EUR 435 |
Description: Purified Native Human IgE |
Human Chlamydia pneumoniae IgE,Cpn IgE ELISA Kit |
201-12-2075 |
SunredBio |
96 tests |
EUR 440 |
|
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
Human IgE antibody |
E22NH04-1 |
EnoGene |
100ug |
EUR 343 |
Anti-IgE antibody |
STJ400104 |
St John's Laboratory |
1 mg |
EUR 446 |
Description: Immunoglobulin E (IgE) is a class of antibody that has only been found in mammals. It plays an important role in allergy and defence against parasites. Although IgE is typically the least abundant isotype - blood serum IgE levels in a normal individual are only 0.05 % of the IgG concentration - it is capable of triggering the most powerful immune reactions. |
fumigatus allergens permits a discrimination between ABPA and A. fumigatus sensitization with excessive specificity and sensitivity demonstrating the facility of recombinant allergens for the differential analysis of A. fumigatus-related pulmonary problems.