Ran Activation Assay Kit, Trial Size

STA-409-T 5 assays
EUR 403
Description: Our Ran Activation Assay uses visible agarose beads to selectively precipitate the active form of Ran protein. The precipitated small GTPase is then detected by Western blot using a Ran-specific antibody included in the kit.

Pan-Ras Activation Assay Kit, Trial Size

STA-400-T 5 assays
EUR 403
Description: Our Ras Activation Assays use visible agarose beads to selectively precipitate the active form of specific Ras protein of interest. The precipitated small GTPase is then detected by Western blot using a target-specific antibody included in the kit. Assays are available to detect specific isoforms H-Ras, K-Ras, and N-Ras, as well as a Pan-Ras assay that detects all three isoforms.

T-cell-specific surface glycoprotein CD28/CD28

E21-I67 10ug
EUR 343

anti-CD3 T-cell

501-A-01mg 0,1 mg
EUR 267.5
Description: anti-CD3 T-cell

anti-CD3 T-cell

501-A-1000ug 1000 ug
EUR 1282.5
Description: anti-CD3 T-cell

CD3, T-Cell; Polyclonal

A00030 6 ml
EUR 213

CD3, T-Cell; Polyclonal

A00030-0100 100 ml
EUR 2250

CD3, T-Cell; Polyclonal

A00030.0025 25 ml
EUR 621

CD3, T-Cell; Polyclonal

A20030 2 ml
EUR 130

Rac1 Activation Assay Kit, Trial Size

STA-401-1-T 5 assays
EUR 403
Description: Our Rac Activation Assays use visible agarose beads to selectively precipitate the active form of Rac1 or Rac2. The precipitated small GTPase is then detected by Western blot using a Rac1- or Rac2-specific antibody included in the kit.

Rac2 Activation Assay Kit, Trial Size

STA-401-2-T 5 assays
EUR 403
Description: Our Rac Activation Assays use visible agarose beads to selectively precipitate the active form of Rac1 or Rac2. The precipitated small GTPase is then detected by Western blot using a Rac1- or Rac2-specific antibody included in the kit.

RhoA Activation Assay Kit, Trial Size

STA-403-A-T 5 assays
EUR 403
Description: Our Rho Activation Assays use visible agarose beads to selectively precipitate the active form of RhoA, RhoB or RhoC. The precipitated small GTPase is then detected by Western blot using a RhoA-, RhoB- or RhoC-specific antibody included in the kit.

RhoB Activation Assay Kit, Trial Size

STA-403-B-T 5 assays
EUR 403
Description: Our Rho Activation Assays use visible agarose beads to selectively precipitate the active form of RhoA, RhoB or RhoC. The precipitated small GTPase is then detected by Western blot using a RhoA-, RhoB- or RhoC-specific antibody included in the kit.

RhoC Activation Assay Kit, Trial Size

STA-403-C-T 5 assays
EUR 403
Description: Our Rho Activation Assays use visible agarose beads to selectively precipitate the active form of RhoA, RhoB or RhoC. The precipitated small GTPase is then detected by Western blot using a RhoA-, RhoB- or RhoC-specific antibody included in the kit.

Rap1 Activation Assay Kit, Trial Size

STA-406-1-T 5 assays
EUR 403
Description: Our Rap Activation Assays use visible agarose beads to selectively precipitate the active form of Rap1 or Rap2. The precipitated small GTPase is then detected by Western blot using a Rap1- or Rap2-specific antibody included in the kit.

Rap2 Activation Assay Kit, Trial Size

STA-406-2-T 5 assays
EUR 403
Description: Our Rap Activation Assays use visible agarose beads to selectively precipitate the active form of Rap1 or Rap2. The precipitated small GTPase is then detected by Western blot using a Rap1- or Rap2-specific antibody included in the kit.

Arf1 Activation Assay Kit, Trial Size

STA-407-1-T 5 assays
EUR 403
Description: Our Arf Activation Assays use visible agarose beads to selectively precipitate the active form of Arf1 or Arf 6. The precipitated small GTPase is then detected by Western blot using an Arf1- or Arf6-specific antibody included in the kit.

Arf6 Activation Assay Kit, Trial Size

STA-407-6-T 5 assays
EUR 403
Description: Our Arf Activation Assays use visible agarose beads to selectively precipitate the active form of Arf1 or Arf 6. The precipitated small GTPase is then detected by Western blot using an Arf1- or Arf6-specific antibody included in the kit.

H-Ras Activation Assay Kit, Trial Size

STA-400-H-T 5 assays
EUR 403
Description: Our Ras Activation Assays use visible agarose beads to selectively precipitate the active form of specific Ras protein of interest. The precipitated small GTPase is then detected by Western blot using a target-specific antibody included in the kit. Assays are available to detect specific isoforms H-Ras, K-Ras, and N-Ras, as well as a Pan-Ras assay that detects all three isoforms.

K-Ras Activation Assay Kit, Trial Size

STA-400-K-T 5 assays
EUR 403
Description: Our Ras Activation Assays use visible agarose beads to selectively precipitate the active form of specific Ras protein of interest. The precipitated small GTPase is then detected by Western blot using a target-specific antibody included in the kit. Assays are available to detect specific isoforms H-Ras, K-Ras, and N-Ras, as well as a Pan-Ras assay that detects all three isoforms.

N-Ras Activation Assay Kit, Trial Size

STA-400-N-T 5 assays
EUR 403
Description: Our Ras Activation Assays use visible agarose beads to selectively precipitate the active form of specific Ras protein of interest. The precipitated small GTPase is then detected by Western blot using a target-specific antibody included in the kit. Assays are available to detect specific isoforms H-Ras, K-Ras, and N-Ras, as well as a Pan-Ras assay that detects all three isoforms.

CD3 (activation epitope) Antibody

abx139107-01mg 0.1 mg
EUR 384

Rat T-cell-specific surface glycoprotein CD28(CD28) ELISA kit

CSB-EL004913RA-24T 1 plate of 24 wells
EUR 165
Description: Quantitativesandwich ELISA kit for measuring Rat T-cell-specific surface glycoprotein CD28 (CD28) in samples from serum, plasma, tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rat T-cell-specific surface glycoprotein CD28(CD28) ELISA kit

1-CSB-EL004913RA
  • EUR 703.00
  • EUR 4843.00
  • EUR 2570.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Rat T-cell-specific surface glycoprotein CD28(CD28) in samples from serum, plasma, tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human CD28/ T-cell-specific surface glycoprotein CD28 ELISA Kit

E0415Hu 1 Kit
EUR 563

Pig T-Cell-Specific Surface Glycoprotein CD28 (CD28) ELISA Kit

abx361281-96tests 96 tests
EUR 825

Rabbit T-Cell-Specific Surface Glycoprotein CD28 (CD28) ELISA Kit

abx363245-96tests 96 tests
EUR 825

Chicken T-Cell-Specific Surface Glycoprotein CD28 (CD28) ELISA Kit

abx356685-96tests 96 tests
EUR 825

Monkey T-Cell-Specific Surface Glycoprotein CD28 (CD28) ELISA Kit

abx359480-96tests 96 tests
EUR 825

Cow T-Cell-Specific Surface Glycoprotein CD28 (Cd28) ELISA Kit

abx513614-96tests 96 tests
EUR 911

Human T-Cell-Specific Surface Glycoprotein CD28 (CD28) ELISA Kit

abx513616-96tests 96 tests
EUR 707

Mouse T-Cell-Specific Surface Glycoprotein CD28 (Cd28) ELISA Kit

abx513617-96tests 96 tests
EUR 668

Rat T-Cell-Specific Surface Glycoprotein CD28 (Cd28) ELISA Kit

abx513618-96tests 96 tests
EUR 668

Human T-Cell-Specific Surface Glycoprotein CD28 (CD28) ELISA Kit

abx253617-96tests 96 tests
EUR 707

Human CD28(T-cell-specific surface glycoprotein CD28) ELISA Kit

EH0653 96T
EUR 524.1
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.375 ng/ml

Rabbit T- cell- specific surface glycoprotein CD28, CD28 ELISA K

ELI-02296Ra 96 Tests
EUR 928

Rat T cell specific surface glycoprotein CD28(CD28) ELISA kit

E02T0606-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Rat T cell specific surface glycoprotein CD28(CD28) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat T cell specific surface glycoprotein CD28(CD28) ELISA kit

E02T0606-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Rat T cell specific surface glycoprotein CD28(CD28) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat T cell specific surface glycoprotein CD28(CD28) ELISA kit

E02T0606-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rat T cell specific surface glycoprotein CD28(CD28) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human T cell specific surface glycoprotein CD28(CD28) ELISA kit

E01T0606-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Human T cell specific surface glycoprotein CD28(CD28) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human T cell specific surface glycoprotein CD28(CD28) ELISA kit

E01T0606-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Human T cell specific surface glycoprotein CD28(CD28) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human T cell specific surface glycoprotein CD28(CD28) ELISA kit

E01T0606-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Human T cell specific surface glycoprotein CD28(CD28) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat T cell specific surface glycoprotein CD28(CD28) ELISA kit

E06T0606-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Goat T cell specific surface glycoprotein CD28(CD28) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat T cell specific surface glycoprotein CD28(CD28) ELISA kit

E06T0606-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Goat T cell specific surface glycoprotein CD28(CD28) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat T cell specific surface glycoprotein CD28(CD28) ELISA kit

E06T0606-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Goat T cell specific surface glycoprotein CD28(CD28) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit T cell specific surface glycoprotein CD28(CD28) ELISA kit

E04T0606-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Rabbit T cell specific surface glycoprotein CD28(CD28) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit T cell specific surface glycoprotein CD28(CD28) ELISA kit

E04T0606-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Rabbit T cell specific surface glycoprotein CD28(CD28) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit T cell specific surface glycoprotein CD28(CD28) ELISA kit

E04T0606-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rabbit T cell specific surface glycoprotein CD28(CD28) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse T cell specific surface glycoprotein CD28(CD28) ELISA kit

E03T0606-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Mouse T cell specific surface glycoprotein CD28(CD28) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse T cell specific surface glycoprotein CD28(CD28) ELISA kit

E03T0606-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Mouse T cell specific surface glycoprotein CD28(CD28) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse T cell specific surface glycoprotein CD28(CD28) ELISA kit

E03T0606-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Mouse T cell specific surface glycoprotein CD28(CD28) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig T cell specific surface glycoprotein CD28(CD28) ELISA kit

E07T0606-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Porcine T cell specific surface glycoprotein CD28(CD28) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig T cell specific surface glycoprotein CD28(CD28) ELISA kit

E07T0606-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Porcine T cell specific surface glycoprotein CD28(CD28) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig T cell specific surface glycoprotein CD28(CD28) ELISA kit

E07T0606-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Porcine T cell specific surface glycoprotein CD28(CD28) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog T cell specific surface glycoprotein CD28(CD28) ELISA kit

E08T0606-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Canine T cell specific surface glycoprotein CD28(CD28) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog T cell specific surface glycoprotein CD28(CD28) ELISA kit

E08T0606-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Canine T cell specific surface glycoprotein CD28(CD28) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog T cell specific surface glycoprotein CD28(CD28) ELISA kit

E08T0606-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Canine T cell specific surface glycoprotein CD28(CD28) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey T cell specific surface glycoprotein CD28(CD28) ELISA kit

E09T0606-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Monkey T cell specific surface glycoprotein CD28(CD28) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey T cell specific surface glycoprotein CD28(CD28) ELISA kit

E09T0606-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Monkey T cell specific surface glycoprotein CD28(CD28) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey T cell specific surface glycoprotein CD28(CD28) ELISA kit

E09T0606-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Monkey T cell specific surface glycoprotein CD28(CD28) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Non-T-cell Activation Linker Protein

20-abx260597
  • EUR 2861.00
  • EUR 328.00
  • EUR 230.00
  • 1 mg
  • 25 ug
  • 5 ug

CytoSelect Cell Transformation Assay (Cell Recovery Compatible), Colorimetric, Trial Size

CBA-135-T 24 assays
EUR 432
Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis.

Guinea pig T cell specific surface glycoprotein CD28(CD28) ELISA kit

E05T0606-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Guinea pig T cell specific surface glycoprotein CD28(CD28) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig T cell specific surface glycoprotein CD28(CD28) ELISA kit

E05T0606-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Guinea pig T cell specific surface glycoprotein CD28(CD28) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig T cell specific surface glycoprotein CD28(CD28) ELISA kit

E05T0606-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Guinea pig T cell specific surface glycoprotein CD28(CD28) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

CD3 activation epitope Antibody (FITC)

abx140488-01mg 0.1 mg
EUR 425

CD3 activation epitope Antibody (APC)

abx140478-01mg 0.1 mg
EUR 481

CD3 (activation epitope) Antibody (PE)

abx139119-01mg 0.1 mg
EUR 481

CytoSelect 96-Well Cell Transformation Assay (Cell Recovery Compatible, Fluorometric), Trial Size

CBA-140-T 24 assays
EUR 456
Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis.

Recombinant human T-cell-specific surface glycoprotein CD28

P1655 100ug Ask for price
Description: Recombinant protein for human T-cell-specific surface glycoprotein CD28

Rac1 Activation Assay

STA-401-1 20 assays
EUR 757
Description: Our Rac Activation Assays use visible agarose beads to selectively precipitate the active form of Rac1 or Rac2. The precipitated small GTPase is then detected by Western blot using a Rac1- or Rac2-specific antibody included in the kit.

Rac2 Activation Assay

STA-401-2 20 assays
EUR 757
Description: Our Rac Activation Assays use visible agarose beads to selectively precipitate the active form of Rac1 or Rac2. The precipitated small GTPase is then detected by Western blot using a Rac1- or Rac2-specific antibody included in the kit.

Cdc42 Activation Assay

STA-402 20 assays
EUR 757
Description: Our Cdc42 Activation Assays use visible agarose beads to selectively precipitate the active form of Cdc42 protein. The precipitated small GTPase is then detected by Western blot using a Cdc42-specific antibody included in the kit.

RhoA Activation Assay

STA-403-A 20 assays
EUR 757
Description: Our Rho Activation Assays use visible agarose beads to selectively precipitate the active form of RhoA, RhoB or RhoC. The precipitated small GTPase is then detected by Western blot using a RhoA-, RhoB- or RhoC-specific antibody included in the kit.

RhoB Activation Assay

STA-403-B 20 assays
EUR 757
Description: Our Rho Activation Assays use visible agarose beads to selectively precipitate the active form of RhoA, RhoB or RhoC. The precipitated small GTPase is then detected by Western blot using a RhoA-, RhoB- or RhoC-specific antibody included in the kit.

RhoC Activation Assay

STA-403-C 20 assays
EUR 757
Description: Our Rho Activation Assays use visible agarose beads to selectively precipitate the active form of RhoA, RhoB or RhoC. The precipitated small GTPase is then detected by Western blot using a RhoA-, RhoB- or RhoC-specific antibody included in the kit.

Arf1 Activation Assay

STA-407-1 20 assays
EUR 757
Description: Our Arf Activation Assays use visible agarose beads to selectively precipitate the active form of Arf1 or Arf 6. The precipitated small GTPase is then detected by Western blot using an Arf1- or Arf6-specific antibody included in the kit.

Arf6 Activation Assay

STA-407-6 20 assays
EUR 757
Description: Our Arf Activation Assays use visible agarose beads to selectively precipitate the active form of Arf1 or Arf 6. The precipitated small GTPase is then detected by Western blot using an Arf1- or Arf6-specific antibody included in the kit.

Ral Activation Assay

STA-408 20 assays
EUR 757
Description: Our Ral Activation Assay uses visible agarose beads to selectively precipitate the active form of Ral protein. The precipitated small GTPase is then detected by Western blot using a Ral-specific antibody included in the kit.

Ran Activation Assay

STA-409 20 assays
EUR 757
Description: Our Ran Activation Assay uses visible agarose beads to selectively precipitate the active form of Ran protein. The precipitated small GTPase is then detected by Western blot using a Ran-specific antibody included in the kit.

Anti-CD3/CD28 stimulus for human PBMC

CT372 50 tests
EUR 118

T-cell Activation Antigen CD27 (CD27) Antibody

20-abx111471
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

T-cell Activation Antigen CD27 (CD27) Antibody

20-abx306428
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

T-cell Activation Antigen CD27 (CD27) Antibody

20-abx001588
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Recombinant Human Non-T-cell Activation Linker

7-05734 5µg Ask for price

Recombinant Human Non-T-cell Activation Linker

7-05735 25µg Ask for price

Recombinant Human Non-T-cell Activation Linker

7-05736 1mg Ask for price

Non-T-Cell Activation Linker (NTAL) Antibody

abx139940-01mg 0.1 mg
EUR 425

Non-T-Cell Activation Linker (NTAL) Antibody

abx139941-01mg 0.1 mg
EUR 425

Non-T-Cell Activation Linker (NTAL) Antibody

abx140049-01mg 0.1 mg
EUR 425