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PROTEINASE K Molecular Biology Grade
Abstract Infectious proteins (prions) are, mockingly, outlined by their resistance to proteolytic digestion. A defining attribute of the transmissible isoform of the prion protein (PrPSc) is its partial resistance to proteinase K (PK) digestion. Diagnosis of prion illness usually depends upon immunodetection of PK-digested PrPSc by Western blot, ELISA or immunohistochemical Read more…