hedgehog pathway

Desert Hedgehog
MO15112 500 ug
EUR 513

Sonic Hedgehog
PR15000 25 ug
EUR 383

Sonic Hedgehog
PR15000CF 25 ug
EUR 383

Sonic Hedgehog
GT15032 100 ug
EUR 526

Desert Hedgehog
GT15067 100 ug
EUR 526

Vismodegib (Hedgehog inhibitor)
SIH-565-25MG 25 mg
EUR 171
Description: The substance Vismodegib is a hedgehog inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is off-white powder which is May be dissolved in DMSO (200 mg/ml); or ethanol (10 mg/ml, warm).

Vismodegib (Hedgehog inhibitor)
SIH-565-5MG 5 mg
EUR 126
Description: The substance Vismodegib is a hedgehog inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is off-white powder which is May be dissolved in DMSO (200 mg/ml); or ethanol (10 mg/ml, warm).

Sonic Hedgehog/Shh
E21-100 10ug
EUR 343

Sonic Hedgehog/Shh
E21-H69 10ug
EUR 343

rHu Indian Hedgehog
AK9975-0005 5µg Ask for price

rHu Indian Hedgehog
AK9975-0025 25µg Ask for price

rHu Indian Hedgehog
AK9975-0100 100µg Ask for price

rHu Indian Hedgehog
AK9975-1000 1mg Ask for price

anti-Sonic Hedgehog
YF-PA24696 50 ul
EUR 334
Description: Mouse polyclonal to Sonic Hedgehog

Sonic Hedgehog protein
30R-2426 25 ug
EUR 383
Description: Purified recombinant Human Sonic Hedgehog protein

Sonic Hedgehog protein
30R-2432 25 ug
EUR 405
Description: Purified recombinant Mouse Sonic Hedgehog protein

Sonic hedgehog protein
30R-3329 50 ug
EUR 327
Description: Recombinant Human Sonic hedgehog protein

Sonic Hedgehog protein
30R-AS052 25 ug
EUR 273
Description: Purified recombinant Human Sonic Hedgehog protein

Sonic Hedgehog protein
30R-AS053A 25 ug
EUR 295
Description: Purified recombinant Human Sonic Hedgehog protein

Sonic Hedgehog antibody
70R-7123 50 ug
EUR 467
Description: Rabbit polyclonal Sonic Hedgehog antibody

IDO Pathway inhibitor
2746-250
EUR 327

IDO Pathway inhibitor
2746-50
EUR 120

Cyclopamine (Hedgehog signaling blocker)
SIH-226-1MG 1 mg
EUR 135
Description: The substance Cyclopamine is a hedgehog signaling blocker. It is synthetically produced and has a purity of >98%. The pure substance is white solid which is soluble to 5 mM in ethanol.

Cyclopamine (Hedgehog signaling blocker)
SIH-226-5MG 5 mg
EUR 345
Description: The substance Cyclopamine is a hedgehog signaling blocker. It is synthetically produced and has a purity of >98%. The pure substance is white solid which is soluble to 5 mM in ethanol.

Sonic Hedgehog, C24II, Human
HY-P7407 50ug
EUR 486

Sonic Hedgehog, C24IVI, Human
HY-P7408 10ug
EUR 234

Sonic Hedgehog, C25II, Mouse
HY-P7409 50ug
EUR 486

Human Sonic Hedgehog Antibody
32994-05111 150 ug
EUR 261

Mouse Sonic Hedgehog Antibody
33142-05111 150 ug
EUR 261

Human Sonic Hedgehog Antibody
33215-05111 150 ug
EUR 261

Sonic Hedgehog Rabbit mAb
A12695-100ul 100 ul
EUR 410

Sonic Hedgehog Rabbit mAb
A12695-200ul 200 ul
EUR 571

Sonic Hedgehog Rabbit mAb
A12695-20ul 20 ul
EUR 221

Sonic Hedgehog Rabbit mAb
A12695-50ul 50 ul
EUR 287

Hedgehog Acyltransferase (HHAT) Antibody
abx032545-400ul 400 ul
EUR 523

Hedgehog Acyltransferase (HHAT) Antibody
abx032545-80l 80 µl
EUR 286

Recombinant Human Sonic HedgeHog
7-01477 5µg Ask for price

Recombinant Human Sonic HedgeHog
7-01478 25µg Ask for price

Recombinant Human Sonic HedgeHog
7-01479 1mg Ask for price

Recombinant Mouse Sonic HedgeHog
7-01483 5µg Ask for price

Recombinant Mouse Sonic HedgeHog
7-01484 25µg Ask for price

Recombinant Mouse Sonic HedgeHog
7-01485 1mg Ask for price

Recombinant Human Desert HedgeHog
7-01489 5µg Ask for price

Recombinant Human Desert HedgeHog
7-01490 25µg Ask for price

Recombinant Human Desert HedgeHog
7-01491 1mg Ask for price

Desert HedgeHog (C23II) Protein
20-abx260759
  • EUR 3418.00
  • EUR 328.00
  • EUR 230.00
  • 1 mg
  • 25 ug
  • 5 ug

Desert HedgeHog (C23II) Protein
20-abx261648
  • EUR 3418.00
  • EUR 328.00
  • EUR 230.00
  • 1 mg
  • 25 ug
  • 5 ug

Desert HedgeHog (C23II) Protein
20-abx261685
  • EUR 3418.00
  • EUR 328.00
  • EUR 230.00
  • 1 mg
  • 25 ug
  • 5 ug

Anti-Sonic Hedgehog (1B11)
YF-MA15408 100 ug
EUR 363
Description: Mouse monoclonal to Sonic Hedgehog

Sonic Hedgehog Blocking Peptide
33R-7837 100 ug
EUR 180
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of SHH antibody, catalog no. 70R-7123

Sonic Hedgehog Recombinant Protein
40-701 5 ug
EUR 259.25
Description: Members of the Hedgehog (Hh) family are highly conserved proteins that are widely represented throughout the animal kingdom. The three known mammalian Hh proteins, Sonic (Shh), Desert (Dhh) and Indian (Ihh), are structurally related, and share a high degree of amino acid sequence identity (e.g. Shh and Ihh are 93% identical). The biologically active form of each Hh molecule is obtained by autocatalytic cleavage of their precursor proteins, and each corresponds to approximately one half of the N-terminal portion of the precursor molecule. Although Hh proteins have unique expression patterns and distinct biological roles within their respective regions of secretion, they use the same signaling pathway and can be substituted for one another in experimental systems. Recombinant Murine Sonic Hedgehog is a 20.0 kDa protein consisting of 176 amino acid residues, including an N-terminal Ile-Val-Ile sequence substituted for the naturally occurring, chemically modified Cys residue.

Sonic Hedgehog Recombinant Protein
96-689 0.05 mg
EUR 432.5
Description: Sonic hedgehog protein (SHH) is also known as HHG-1, which belongs to the hedgehog family. SHH is expressed in fetal intestine, liver, lung, and kidney and not expressed in adult tissues. Sonic hedgehog protein can be cleavage into sonic hedgehog protein N-product and sonic hedgehog protein C-product by autolysis. SHH binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO. Also regulates another target, the gli oncogene. Intercellular signal essential for a variety of patterning events during development. The C-terminal domain displays an autoproteolysis activity and a cholesterol transferase activity. The N-product is the active species in both local and long-range signaling, whereas the C-product has no signaling activity.

Sonic Hedgehog Recombinant Protein
91-073 0.05 mg
EUR 542.75
Description: Sonic Hedgehog Homolog (SHH) belongs to a three-protein family called Hedgehog. The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH). Hedgehog proteins are key signaling molecules in embryonic development. SHH is expressed in various embryonic tissues and plays critical roles in regulating the patterning of many systems, such as limbs and brain. SHH also plays an important role in adult, including the division of adult stem cells and the development of certain cancers and other diseases. Human SHH is expressed as a 45kDa precursor, and undergoes a series of processing during secretion. After the removal of the signal peptide, a protease within the C-terminal domain catalyzes the cleavage of SHH into a 20 kDa N-terminal signaling domain (SHH-N) and a 25 kDa C-terminal domain (SHH-C). SHH-N has the “all signaling” capability. SHH-N binds to the 12 pass transmembrane protein Patched (Ptc) on cell surface, which releases the repression of the activity of Smoothened (Smo), a G-protein coupled receptor, by Ptc.

Sonic Hedgehog Recombinant Protein
91-083 0.05 mg
EUR 595.25
Description: Sonic Hedgehog Homolog (SHH) belongs to a three-protein family called hedgehog. The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH). Hedgehog proteins are key signaling molecules in embryonic development. SHH is expressed in various embryonic tissues and plays critical roles in regulating the patterning of many systems, such as limbs and brain. SHH also plays an important role in adult, including the division of adult stem cells and the development of certain cancers and other diseases. Human SHH is expressed as a 45kDa precursor, and undergoes a series of processing during secretion. After the removal of the signal peptide, a protease within the C-terminal domain catalyzes the cleavage of SHH into a 20 kDa N-terminal signaling domain (SHH-N) and a 25 kDa C-terminal domain (SHH-C). SHH-N has the “all signaling” capability. SHH-N binds to the 12 pass transmembrane protein Patched (Ptc) on cell surface, which releases the repression of the activity of Smoothened (Smo), a G-protein coupled receptor, by Ptc.

Sonic Hedgehog Recombinant Protein
92-281 0.05 mg
EUR 542.75
Description: Mouse Sonic Hedgehog Homolog (SHH) belongs to a three-protein family called Hedgehog. The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH). Hedgehog proteins are key signaling molecules in embryonic development. SHH is expressed in various embryonic tissues and plays critical roles in regulating the patterning of many systems, such as limbs and brain. SHH also plays an important role in adult, including the division of adult stem cells and the development of certain cancers and other diseases.Mouse Shh is synthesized as a 437 aa precursor that contains a 24 aa signal sequence and a 413 aa mature region. The mature region is autocatalytically processed into a nonglycosylated, 20 kDa, 174 aa N­terminal fragment (Shh­N), and a catalytic­processing,glycosylated, 34 kDa, 239 aa C­terminal fragment. The 20 kDa Shh­N fragment is the core of the active hedgehog molecule. Mouse Shh­N is 99%, 98%, and 100% aa identical to human, rat and gerbil Shh­N, respectively.

Sonic Hedgehog Recombinant Protein
92-284 0.05 mg
EUR 542.75
Description: Mouse Sonic Hedgehog Homolog (SHH) belongs to a three-protein family called Hedgehog. The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH). Hedgehog proteins are key signaling molecules in embryonic development. SHH is expressed in various embryonic tissues and plays critical roles in regulating the patterning of many systems, such as limbs and brain. SHH also plays an important role in adult, including the division of adult stem cells and the development of certain cancers and other diseases.Mouse Shh is synthesized as a 437 aa precursor that contains a 24 aa signal sequence and a 413 aa mature region. The mature region is autocatalytically processed into a nonglycosylated, 20 kDa, 174 aa N­terminal fragment (Shh­N), and a catalytic­processing,glycosylated, 34 kDa, 239 aa C­terminal fragment. The 20 kDa Shh­N fragment is the core of the active hedgehog molecule. Mouse Shh­N is 99%, 98%, and 100% aa identical to human, rat and gerbil Shh­N, respectively.

Human Calcium Regulation Pathway
HCAR-I 1 set
EUR 548

Human Notch Signaling Pathway
HNOT-I 1 set
EUR 548

Hh Signaling Pathway Antagonist
1659-1
EUR 180

Recombinant Hedgehog Homolog, Sonic (SHH)
4-RPB831Hu01
  • EUR 458.40
  • EUR 226.00
  • EUR 1444.00
  • EUR 548.00
  • EUR 996.00
  • EUR 370.00
  • EUR 3460.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Hedgehog Homolog, Sonic expressed in: E.coli