Human IGF-1 LR3

SP-89927-100 100 ug
EUR 225

LR3-IGF-1 Recombinant Protein

91-017 0.05 mg
EUR 364.25
Description: Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contains the N- and C-terminal propeptide regions. Mature human IGF-I consisting of 70 amino acids has 94% identity with mouse IGF-I and exhibits cross-species activity. IGF-1 binds IGF-IR, IGF-IIR, and the insulin receptor and plays a key role in cell cycle progression, cell proliferation and tumor progression. IGF-1 expression is regulated by growth hormone. R3 IGF-1 is an 83 amino acid analog of IGF-1 comprising the complete human IGF-1 sequence with the substitution of an Arg (R) for the Glu(E) at position three, hence R3, and a 13 amino acid extension peptide at the N terminus. R3 IGF-1 has been produced with the purpose of increasing biological activity. R3 IGF-1 is significantly more potent than human IGF-I in vitro.

OryzaExp? IGF-1 LR3, Human Recombinant

P1399-100
EUR 175

Human LR3 IGF-I ELISA

BEK-2233-1P 1 Plate Kit
EUR 529

Human LR3 IGF-I ELISA

BEK-2233-2P 2 Plate Kit
EUR 900

IGF-I LR3 Recombinant Protein

40-623 200 ug
EUR 259.25
Description: The IGFs are mitogenic, polypeptide growth factors that stimulate the proliferation and survival of various cell types, including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar to insulin by structure and function, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), but IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contain N-terminal and C-terminal propeptide regions. Recombinant human IGF-I and IGF-II are globular proteins containing 70 and 67 amino acids, respectively, and 3 intra-molecular disulfide bonds. IGF-I LR3 is a recombinant analog of human IGF-I comprised of the complete IGF-I sequence, with an Arginine substitution for the third position Glutamic acid, and a 13 amino acid length N terminus peptide extension. Specifically engineered for higher biological potency in vitro, IGF-I LR3 has an increased half-life and a binding aversion to native proteins within the body that make it ideal for both research and large-scale culturing. Recombinant Human IGF-I LR3 is a 9.1 kDa, single, non-glycosylated polypeptide chain containing 83 amino acid residues.

Recombinant Human LR3 Insulin-Like Growth Factor I/LR3-IGF-1 (MG)

C023-10ug 10ug
EUR 100
Description: Lyophilized from a 0.2 μm filtered solution of 300mM HAc-NaAc, pH 6.5.

Recombinant Human LR3 Insulin-Like Growth Factor I/LR3-IGF-1 (MG)

C023-1mg 1mg
EUR 608
Description: Lyophilized from a 0.2 μm filtered solution of 300mM HAc-NaAc, pH 6.5.

Recombinant Human LR3 Insulin-Like Growth Factor I/LR3-IGF-1 (MG)

C023-500ug 500ug
EUR 440
Description: Lyophilized from a 0.2 μm filtered solution of 300mM HAc-NaAc, pH 6.5.

Recombinant Human LR3 Insulin-Like Growth Factor I/LR3-IGF-1 (MG)

C023-50ug 50ug
EUR 192
Description: Lyophilized from a 0.2 μm filtered solution of 300mM HAc-NaAc, pH 6.5.

Human LR3 IGF-I (Receptor Grade)

BU020 20 µg
EUR 253

Human LR3 IGF-I (Receptor Grade)

BU100 100 µg
EUR 346

Human LR3 IGF-I monoclonal antibody

MAN100 100 µg
EUR 299

Human LR3 IGF-I (Media Grade)

AM001 1 mg
EUR 438

Human LR3 IGF-I (Media Grade)

AM010 10 mg
EUR 1274

Biotinylated Human LR3 IGF-I monoclonal antibody

MAO100 100 µg
EUR 299

IGF-I-LR3 Recombinant Protein (Animal Free)

40-711 200 ug
EUR 269.75
Description: The IGFs are mitogenic, polypeptide growth factors that stimulate the proliferation and survival of various cell types, including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar to insulin by structure and function, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), but IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contain N-terminal and C-terminal propeptide regions. Recombinant human IGF-I and IGF-II are globular proteins containing 70 and 67 amino acids, respectively, and 3 intra-molecular disulfide bonds. IGF-I LR3 is a recombinant analog of human IGF-I comprised of the complete IGF-I sequence, with an Arginine substitution for the third position Glutamic acid, and a 13 amino acid length N terminus peptide extension. Specifically engineered for higher biological potency in vitro, IGF-I LR3 has an increased half-life and a binding aversion to native proteins within the body that make it ideal for both research and large-scale culturing. Recombinant Human IGF-I LR3 is a 9.1 kDa, single, non-glycosylated polypeptide chain containing 83 amino acid residues.

Human Insulin Like Growth Factor 1 (IGF-1) ELISA Kit, 96 tests, quantitative

100-600-IGF 1 kit
EUR 712

Mouse Insulin Like Growth Factor 1 (IGF-1) ELISA Kit, 96 tests, quantitative

100-605-IGF 1 kit
EUR 712

Rat Insulin Like Growth Factor 1 (IGF-1) ELISA Kit, 96 tests, quantitative

100-610-IGF 1 kit
EUR 712

IGF-1-Fc

E13-m003-1 10μg
EUR 291

IGF-1, human recombinant

P1016-.1 100 µg
EUR 763
Description: Insulin-like growth factor I (IGF-1) is a polypeptide endocrine hormone structurally similar to insulin and is mainly produced in the liver when stimulated by growth hormone. IGF-1 is a growth factor that stimulates the proliferation of various cell types including muscle, bone, and cartilage tissue

Canine IGF-1 Recombinant Protein

R00148-1 5ug/vial
EUR 259
Description: Insulin-like growth factor 1 (IGF-1) is a primary mediator of the effects of growth hormone (GH) and has growth-promoting effects on almost every cell in the body. IGF-1 can also regulate cell growth and development, especially in nerve cells, as well as cellular DNA synthesis. Canine IGF-1 Recombinant Protein is purified insulin-like growth factor 1 (IGF-1) produced in yeast.

Pig Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) ELISA kit

E07I0420-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Porcine Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) ELISA kit

E07I0420-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Porcine Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) ELISA kit

E07I0420-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Porcine Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) ELISA kit

E08I0420-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Canine Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) ELISA kit

E08I0420-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Canine Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) ELISA kit

E08I0420-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Canine Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) ELISA kit

E06I0420-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Goat Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) ELISA kit

E06I0420-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Goat Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) ELISA kit

E06I0420-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Goat Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) ELISA kit

E03I0420-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Mouse Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) ELISA kit

E03I0420-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Mouse Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) ELISA kit

E03I0420-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Mouse Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) ELISA kit

E04I0420-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Rabbit Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) ELISA kit

E04I0420-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Rabbit Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) ELISA kit

E04I0420-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rabbit Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) ELISA kit

E02I0420-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Rat Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) ELISA kit

E02I0420-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Rat Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) ELISA kit

E02I0420-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rat Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) ELISA kit

E01I0420-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Human Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) ELISA kit

E01I0420-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Human Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) ELISA kit

E01I0420-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Human Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) ELISA kit

E09I0420-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Monkey Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) ELISA kit

E09I0420-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Monkey Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) ELISA kit

E09I0420-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Monkey Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) ELISA kit

E05I0420-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Guinea pig Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) ELISA kit

E05I0420-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Guinea pig Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) ELISA kit

E05I0420-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Guinea pig Insulin-like Growth Factors 1 Long R3 (IGF-1 LR3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

IGF-II, human recombinant

P1017-1 1 mg
EUR 1998
Description: Insulin-like Growth Factor-II (IGF-II) is a polypeptide endocrine hormone structurally similar to insulin and belongs to insulin-like growth factor family.

Recombinant Human IGF-II Protein

PROTP01344-1 50ug
EUR 317
Description: The IGFs are mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar by structure and function to insulin, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), but, IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contain N-terminal and C-terminal propeptide regions. Recombinant human IGF-I and IGF-II are globular proteins containing 70 and 67 amino acids, respectively, and 3 intra-molecular disulfide bonds.

Recombinant Murine IGF-I Protein

PROTP05017-1 50ug
EUR 317
Description: The IGFs are mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar by structure and function to insulin, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), but, IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contain N-terminal and C-terminal propeptide regions. Recombinant murine IGF-I is a 7.6 kDa globular protein containing amino acids including 3 intra-molecular disulfide bonds.

Recombinant Human IGF-I Protein

PROTP05019-1 500ug
EUR 317
Description: The IGFs are mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar by structure and function to insulin, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), but, IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contain N-terminal and C-terminal propeptide regions. Recombinant human IGF-I and IGF-II are globular proteins containing 70 and 67 amino acids, respectively, and 3 intra-molecular disulfide bonds.

Recombinant Human IGF-BP1 Protein

PROTP08833-1 25ug
EUR 317
Description: IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP1 is a 25.4 kDa cysteine-rich secreted protein expressed in liver, deciduas, and kidneys and is the most abundant IGF-BP in amniotic fluid. Levels of IGF-BP1 in serum are lowest after food. IGF-BP1 binds to both IGF-I and IGF-II with equal affinity. Phosphorylated IGF-BP1 hinders IGF actions, where as nonphosphorylated IGF-BP1 is stimulatory. Recombinant human IGF-BP1 is a 25.4 kDa protein consisting of 235 amino acid residues (Isoform A).

Recombinant Human IGF-BP4 Protein

PROTP22692-1 20ug
EUR 317
Description: IGF-BPs control the distribution, function and activity of IGFs in various cell tissues and body fluids. IGF-BP4 is the major IGF-BP produced by osteoblasts, and is also found in the epidermis, ovarian follicles, and other tissues. IGF-BP4 inhibits the activity of IGF-I and IGF-II by binding in a manner that results in the formation of complexes with reduced ability to signal through cell surface IGF receptors. IGF-BP4 can inhibit the growth of chick pelvis cartilage and HT29 colon adenocarcinoma cells by blocking the mitogenic actions of IGFs, and has also been shown to reduce colony formation by colorectal cancer cells via an IGF independent pathway. The biological effects of IGF-BP4 can be regulated by Pregnancy Associated Plasma Protein A (PAPP-A), which reduces IGF-BP4/IGF binding affinity by proteolytically cleaving IGF-BP4. The modulation of IGF-BP4 activity by PAPP-A is an important component in the regulation of ovarian folliculogenesis and in the growth inhibition of responding ovarian cancer cells. Recombinant human IGF-BP4 is a 25.8 kDa protein consisting of 237 amino acid residues including the IGF-BP domain and thyroglobulin type-I domain.

*Manufactured using (BTI-Tn-5B1-4) cells under license from the Boyce Thompson Institute for Plant Research, Inc.

Recombinant Human IGF-BP5 Protein

PROTP24593-1 25ug
EUR 317
Description: IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP5 is a 28.6 kDa cysteine-rich secreted protein produced by vascular smooth muscle cells. It is the major IGF-binding protein present in bone tissue and helps potentiate the action of IGF-I on smooth muscle cells, fibroblasts or osteoblasts. Data shows that IGFBP-5 acts as a growth inhibitor and pro-apoptotic agent in breast cancer cells. IGFBP-5 overexpressing mice show an increase in neonatal mortality, reduced female fertility, whole-body growth inhibition and retarded muscle development. Recombinant human IGF-BP5 is a 28.6 kDa protein consisting of 253 amino acid residues.

Human Insulin-like Growth Factor 1 (IGF-1) AssayMax ELISA Kit

EI1001-1 96 Well Plate
EUR 477

Mouse Insulin-like Growth Factor 1 (IGF-1) AssayMax ELISA Kit

EMI1001-1 96 Well Plate
EUR 477

Anti-IGF-1R (Ab-1161) Antibody

A00070-1 100ul
EUR 397
Description: Rabbit Polyclonal IGF-1R (Ab-1161) Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat.