Four amino acids as serum biomarkers for anti-asthma effects in the ovalbumin-induced asthma mouse model treated with extract of Asparagus cochinchinensis.

The butanol extract of <i>Asparagus cochinchinensis</i> roots fermented with <i>Weissella cibaria</i> (BAW) successfully prevents irritation and transforming of airway within the ovalbumin (OVA)-induced bronchial asthma mannequin. To characterize biomarkers that may predict the anti-asthmatic results induced by BAW therapy, we measured the alteration of endogenous metabolites within the serum of OVA-induced bronchial asthma mice after … Read more

CD19-targeting fusion protein combined with PD1 antibody enhances anti-tumor immunity in mouse models.

In our earlier research, utilizing a B cell vaccine (scFv-Her2), the concentrating on of tumor-associated antigen Her2 (human epidermal progress issue receptor-2) to B cells by way of the anti-CD19 single chain variable fragment (scFv) was proven to enhance tumor-specific immunity, which enhanced tumor management in the prophylactic and therapeutic setting. However, the fusion protein … Read more